Abstract: Four opioid receptors and five dopamine receptors have been described thus far. Drugs that act on the individual receptors within each class have sometimes similar and sometimes different behavioral effects. The underlying principles of drug-receptor interactions are clearly supported in both of these systems, but agonist-antagonist interactions are interestingly different in these two systemsor are they? Attendees will learn something of the history of behavioral pharmacology using drugs that act on these receptors, how behavioral pharmacology can support drug-classification schemes, what can be learned about agonist and antagonist interactions using behavior as an endpoint, how drugs that act on these receptors compare as stimuli, and what is necessary for better understanding of drug-behavior interactions in the future. |