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Cannabis Dose-Effects Across Routes of Administration: Subjective, Performance, and Pharmacokinetic Differences |
| Monday, May 29, 2017 |
| 3:00 PM–3:50 PM |
| Convention Center Four Seasons Ballroom 4 |
| Area: SCI; Domain: Basic Research |
| Instruction Level: Intermediate |
| CE Instructor: Christine E. Hughes, Ph.D. |
| Chair: Christine E. Hughes (University of North Carolina Wilmington) |
| RYAN VANDREY (Johns Hopkins University) |
 Dr. Vandrey is an experimental psychologist with degrees from the University of Delaware (BA) and University of Vermont (Ph.D.). He is currently an Associate Professor at the Johns Hopkins University Behavioral Pharmacology Research Unit (BPRU). Dr. Vandrey's research focuses on the behavioral pharmacology of cannabis (marijuana) with a primary focus of controlled laboratory studies with adult research volunteers, but also includes clinical trials, web-based survey research, and natural history studies with patient populations using cannabis/cannabinoids for therapeutic purposes. His work helped characterize the cannabis withdrawal syndrome, has provided novel data about the comparative pharmacokinetics and corresponding pharmacodynamics of cannabinoids across routes of administration, explored medications that are potential adjuncts to behavior therapy to improve rates of abstinence among individuals trying to quit using cannabis, examined the effects of cannabis on sleep, and provides information about the risks and benefits of medicinal use of cannabis/cannabinoids for various health conditions. |
| Abstract: The use of cannabis (marijuana) for medical and non-medical purposes is expanding worldwide and now includes legal retail outlets for purchasing cannabis products in many areas. Retail cannabis products are varied with respect to dose and intended route of administration, yet the preponderance of scientific data is limited to analysis of the effects of smoked cannabis. This presentation will summarize data from a series of controlled human laboratory studies evaluating the dose effects of oral, smoked, and vaporized cannabis in healthy, non-tolerant individuals. Outcome measures to be described include subjective ratings of drug effects, cardiovascular measures, cannabinoid quantitation in biological fluid, and performance on psychomotor, memory, and divided attention tasks. Implications of the study findings will be discussed with respect to regulation of medical and non-medical cannabis products, drug testing, and education. |
| Target Audience: Masters and Doctoral Level BCBAs |
| Learning Objectives: At the conclusion of the presentation, attendees will be able to: (1) Understand how route of administration alters the time course of cannabis effects; (2) Be able to describe adverse effects of cannabis that can occur at high doses; (3) Understand the relation between blood THC levels and behavioral effects. |
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